Effect of Bisphosphonates on Anticancer Activity in Prostate Cancer Cells

[Effect of bisphosphonates on anticancer activity in prostate cancer cells].

Bisphosphonates are widely used to treat for osteoporosis and have recently been suggested to be effective in preventing tumor metastasis to the bone. One of the mechanisms underlying metastasis inhibition by bisphosphonates has been explained on the basis of the direct effects of these drugs on cancer cells in the bone microenvironment. Here we have focused on the effect of bisphosphonates on ...

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Curcumin (Cur) has been found to be very efficacious against many different types of cancercells. However, the major disadvantage associated with the use of Cur is its low systemicbioavailability. Our present work investigated the toxic effect of encapsulation of Cur in PLGA(poly lactic-coglycolic acid) nanospheres (NCur) on PC3 human cancer prostate cell. In thepresent study, we have investiga...

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Anticancer Activity of Curcumin-Loaded PLGA Nanoparticles on PC3 Prostate Cancer Cells

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Synergistic Anticancer Effect of Paclitaxel and Noscapine on Human Prostate Cancer Cell Lines

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Synergistic Anticancer Effect of Paclitaxel and Noscapine on Human Prostate Cancer Cell Lines

Paclitaxel is the one of the most common chemotherapeutic drugs used for the treatment of prostate cancer. However, its current clinical utility has been limited due to numerous serious side effects and drug resistance. Noscapine is an antitussive opium alkaloid that showed antitumor activity against a variety of cancer while has not exhibited severe side effects. This study investigates the a...

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Effect of Bisphosphonates on Anticancer Activity in Prostate Cancer Cells

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